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RMRC No.

RMRC13376

Order

Strain/Stock Designation

C57BL/6-Cyp11a1^tm10Bcc/Narl

Status

EM| (Cryopreserved Embryos)

Availability

Level4

Pricing

(Embryos)　Industry：*　Academia: 7,066NTD　NSTC: 4,923NTD
(Cryo Recovery)　Industry：*　Academia: 12,618NTD　NSTC: 12,618NTD

Last Update Date

2023/3/22

Analysis Data

Description
Genes &
alleles
Phenotype
Health &
husbandry
References
Specific Term
and Conditions
Construct map

Species

：

laboratory mouse

Strain Type

：

COI (coisogenic strain),MSR (mutant strain)

Mutant Type

：

TM (Target Mutation)

Other Names

：

Cy11a1a FF mice

Background Strain

：

C57BL/6

Strain Description

：

1.	A targeting vector was designed to flanked exon 2 to exon 4 of Cyp11a1 gene with loxP sites and also placed a Frt-flanked neomycin resistance (neo) cassette downstream of exon 4 of of Cyp11a1 gene.
2.	The targeting construct was electroporated into C57BL/6J embryonic stem (ES) cells.

Depositor

：

Bon-Chu Chung

鍾邦柱

：

mbchung@gate.sinica.edu.tw

Allele Symbol	：	Cyp11a1^tm10Bcc

Allele Name	：	cytochrome P450, family 11, subfamily a, polypeptide 1, target mutation 10, Bon-Chu Chung

Allele Description	：






Strain of Origin	：	C57BL/6

Gene Symbol	：	Cyp11a1

Gene Name	：	cytochrome P450, family 11, subfamily a, polypeptide 1

Chromosome	：	9






Genotyping Method	：	Download
Genotyping NLAC	：

Research Application

：

Immunology and Inflammation	Internal/ Organ
Cell and Developmental Biology	Metabolism
Neurobiology Research	Diabetes and Obesity
Endocrine	Reproductive Biology
Genetics Research

Construction Technologies

：

Cre-lox system

FLP-FRT system

Animal Health Reports	：

Colony Maintenance Breeding & Husbandry	：	No

Colony Maintenance Mating System	：	hetero/hemi x wild type

References

：

Specific Terms of Use

：

有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料所獲得之研究成果，不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.

分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應揭露並致謝本材料係由Dr. Bon-Chu Chung, IMB, Academia Sinica所提供

Should the use of this material result in one or more scientific publication(s) the Recipient Investigator agrees to mention and acknowledge Dr. Bon-Chu Chung, IMB, Academia Sinica

分讓申請人向國研院動物中心國家實驗鼠種原庫(NLAC-RMRC)申請本材料時，應附上寄存人簽名之授權分讓同意書作為附件；NLAC- RMRC 在取得寄存人書面同意後，始進行此材料之分讓。
The recipient should obtain a written consent from the depositor of the BIOLOGICAL RESOURCE, prior to NLAC-RMRC accepting the material distribution request.
Depositor Email: mbchung@gate.sinica.edu.tw

Construct Map

：