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RMRC No.

RMRC13343

Order

Strain/Stock Designation

FVB/N-Tg(PGK-HSPD1)Wfs/Narl

Status

EM| (Cryopreserved Embryos)

Availability

Level4

Pricing

(Embryos)　Industry：*　Academia: 7,066NTD　NSTC: 4,923NTD
(Cryo Recovery)　Industry：*　Academia: 12,618NTD　NSTC: 12,618NTD

Last Update Date

2018/1/22

Analysis Data

Description
Genes &
alleles
Phenotype
Health &
husbandry
References
Specific Term
and Conditions
Construct map

Species

：

laboratory mouse

Strain Type

：

COI (coisogenic strain),MSR (mutant strain)

Mutant Type

：

TG (Transgenic)

Other Names

：

Background Strain

：

FVB/N

Strain Description

：

1.	The construct carried transgene was injected into fertilized embryos harvested from FVB/N mice.
2.	This strain overexpressed Human HSPD1 driven by human phosphoglycerate kinase promoter.
3.	There was no significant difference in body weight and serum biochemistry profiles between this strain and wild type.
4.	Articular condrocytes and synovial cells strongly expressed HSPD1. Articular condrocytes density and proliferating activity were significantly increased.
5.	Articular cartilage in the media tibia plateau is thicker in this strain.

Depositor

：

Wang, Feng-Sheng

王逢興

：

wangfs@ms33.hinet.net

Allele Symbol	：	Tg(PGK-HSPD1)Wfs

Allele Name	：	transgenic insertion 9, Wang Feng-Sheng

Allele Description	：






Strain of Origin	：	FVB/N

Gene Symbol	：	HSPD1

Gene Name	：	heat shock protein 1 (chaperonin)

Chromosome	：	UN






Genotyping Method	：	Download
Genotyping NLAC	：

Research Application

：

Apoptosis	Immunology and Inflammation
Metabolism	Diabetes and Obesity
Genetics Research

Construction Technologies

：

Animal Health Reports	：

Colony Maintenance Breeding & Husbandry	：	No

Colony Maintenance Mating System	：	homo x homo

References

：

PubMed ID: 27118120

Specific Terms of Use

：

有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料所獲得之研究成果，不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.

分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應引用下述已發表之論文： J Mol Med (Berl). 2016, 94(7):755-69

Should the use of this material result in one or more scientific
publication(s) the recipient agrees to cite the paper(s)： J Mol Med (Berl). 2016, 94(7):755-69

分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應揭露並致謝本材料係由Core Lab. for Phenomics and Diagnostics, CGMH所提供

Should the use of this material result in one or more scientific publication(s) the Recipient Investigator agrees to mention and acknowledge Core Lab. for Phenomics and Diagnostics, CGMH

Construct Map

：