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RMRC No.

RMRC13406

Order

Strain/Stock Designation

B6.129-Tpt1^tm2Yen/Narl

Status

EM| (Cryopreserved Embryos)

Availability

Level4

Pricing

(Embryos)　Industry：*　Academia: 7,066NTD　NSTC: 4,923NTD
(Cryo Recovery)　Industry：*　Academia: 12,618NTD　NSTC: 12,618NTD

Last Update Date

2023/2/21

Analysis Data

Description
Genes &
alleles
Phenotype
Health &
husbandry
References
Specific Term
and Conditions
Construct map

Species

：

laboratory mouse

Strain Type

：

CON (congenic strain),IS (inbred strain)

Mutant Type

：

TM (Target Mutation)

Other Names

：

TCTP^f/f

Background Strain

：

C57BL/6JNarl

Strain Description

：

The targeting vector was contained a floxed cassette containing both Neo and TK selection marker in intron 2 and the thirdloxP site in intron 4 of the Tpt1 gene. This targeting vector was electroporated into R1 embryonic stem cells. Two positive clones harboring targeted allele, 248 and 280, were further microjnjected into C57BL/6 blastocysts to generated chimeric mice. The mice were backcrossed with C57BL/6 more than 10 generations and maintained in C57BL/6 background.

Homozygous mice are viable and fertile.

Depositor

：

Hsin-Fang Yang-Yen

楊性芳

：

imbyy@gate.sinica.edu.tw

Allele Symbol	：	Tpt1^tm2Yen

Allele Name	：	tumor protein, translationally-controlled 1,target mutation 2, Hsin-Fang Yang-Yen

Allele Description	：






Strain of Origin	：	129svj/ C57BL/6J mixed

Gene Symbol	：	Tpt1

Gene Name	：	tumor protein, translationally-controlled 1

Chromosome	：	14






Genotyping Method	：	Download
Genotyping NLAC	：	Download

Research Application

：

Apoptosis	Cancer
Immunology and Inflammation	Cell and Developmental Biology
Metabolism	Diabetes and Obesity

Construction Technologies

：

Cre-lox system

Animal Health Reports	：

Colony Maintenance Breeding & Husbandry	：

Colony Maintenance Mating System	：	homo x homo

References

：

PubMed ID: 17475776
PubMed ID: 19605695

Specific Terms of Use

：

有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料所獲得之研究成果，不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.

分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應引用下述已發表之論文： (1) Mol Biol Cell. 2007 Jul;18(7):2525-32 (2) J Immunol. 2009 Aug 15;183(4):2373-81

Should the use of this material result in one or more scientific
publication(s) the recipient agrees to cite the paper(s)： (1) Mol Biol Cell. 2007 Jul;18(7):2525-32 (2) J Immunol. 2009 Aug 15;183(4):2373-81

分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應揭露並致謝本材料係由Hsin-Fang, Yang-Yen所提供

Should the use of this material result in one or more scientific publication(s) the Recipient Investigator agrees to mention and acknowledge Hsin-Fang, Yang-Yen

分讓申請人向國研院動物中心國家實驗鼠種原庫(NLAC-RMRC)申請本材料時，應附上寄存人簽名之授權分讓同意書作為附件；NLAC- RMRC 在取得寄存人書面同意後，始進行此材料之分讓。
The recipient should obtain a written consent from the depositor of the BIOLOGICAL RESOURCE, prior to NLAC-RMRC accepting the material distribution request.
Depositor Email: imbyy@gate.sinica.edu.tw

Construct Map

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